Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560932 | 1.00 | GAA (0.37) | GAAP2RX7ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL28437828 | 0.78 | HDAC1 (0.48) | GAAALDH1A1MAPT | |
| SCHEMBL8563081 | 0.76 | KDM4E (0.39) | ALDH1A1CYP2C19 | |
| SCHEMBL8563078 | 0.76 | KDM4E (0.39) | ALDH1A1CYP2C19 | |
| Bromide SCHEMBL8562114 | 0.75 | GAA (0.35) | GAAP2RX7ALDH1A1SMN1; SMN2TSHR | |
| Bromide SCHEMBL8897946 | 0.75 | GAA (0.35) | GAAP2RX7ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7621523 | 0.74 | CRBN (0.53) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7621521 | 0.74 | CRBN (0.53) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7621516 | 0.74 | CRBN (0.53) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8560583 | 0.72 | KMT2A (0.53) | P2RX7ALDH1A1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |