Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1517568 | 0.76 | KMT2A (0.66) | CA1CA2CA12CA9CA4 | |
| SCHEMBL163797 | 0.74 | HTR6 (0.59) | CA1CA2CA12CA9HTR6 | |
| Hydrochloric Acid SCHEMBL2541364 | 0.74 | KMT2A (0.63) | CA1CA2CA12CA9CA4 | |
| SCHEMBL2472588 | 0.73 | CA2 (0.54) | NAMPTCA1CA2CA12CA9 | |
| SCHEMBL8165824 | 0.73 | PKM (0.65) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3833910 | 0.73 | CA1 (0.58) | CA1CA2CA12CA9HTR6 | |
| Hydrochloric Acid SCHEMBL2433519 | 0.73 | KMT2A (0.61) | CA1CA2CA12CA9CA4 | |
| SCHEMBL11514497 | 0.72 | TSHR (0.48) | CA1CA2CA12CA9KMT2A | |
| Bicarbonate SCHEMBL5658794 | 0.71 | KMT2A (0.65) | CA1CA2CA12CA9CA4 | |
| SCHEMBL29196139 | 0.71 | CA1 (0.50) | CA1CA2HTR6CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |