Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.43 |
| ▸ | HTR2B | P41595 | 8/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 7/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8564486 | 0.81 | HTR6 (0.44) | HTR6 | |
| SCHEMBL8562408 | 0.80 | S1PR1 (0.44) | HTR6MLNR | |
| SCHEMBL8561281 | 0.77 | QPCT (0.39) | HTR2CHTR2BHTR6MLNRCYP2D6 | |
| Hydrochloric Acid SCHEMBL8564109 | 0.77 | S1PR1 (0.47) | HTR2CHTR6MLNR | |
| Hydrochloric Acid SCHEMBL8561390 | 0.76 | HTR6 (0.45) | HTR6 | |
| Hydrochloric Acid SCHEMBL8896246 | 0.75 | PRMT1 (0.58) | HTR6 | |
| Hydrochloric Acid SCHEMBL8565324 | 0.75 | PRMT1 (0.58) | HTR6 | |
| Hydrochloric Acid SCHEMBL8566413 | 0.75 | RXRA (0.43) | HTR2CHTR2BHTR6 | |
| Hydrochloric Acid SCHEMBL8559315 | 0.74 | PRMT1 (0.43) | HTR6 | |
| Hydrochloric Acid SCHEMBL8562284 | 0.74 | HTR6 (0.40) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |
| EP-0612741-B1 | Cyclic derivatives, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0612741-A1 | Cyclic derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-08-31 | — | — | EP | disclosed |