Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565325 | 0.93 | PTAFR (0.38) | PTAFR | |
| SCHEMBL8570931 | 0.92 | BMP1 (0.31) | — | |
| SCHEMBL8562710 | 0.92 | PTAFR (0.38) | PTAFR | |
| SCHEMBL8563759 | 0.88 | PTAFR (0.35) | PTAFR | |
| SCHEMBL8565735 | 0.85 | PTAFR (0.39) | PTAFR | |
| SCHEMBL8561481 | 0.85 | PTAFR (0.49) | PTAFR | |
| SCHEMBL8570381 | 0.83 | BMP1 (0.34) | PTAFR | |
| SCHEMBL8567796 | 0.83 | PTAFR (0.38) | PTAFR | |
| SCHEMBL8562738 | 0.81 | PTAFR (0.36) | PTAFR | |
| SCHEMBL8564905 | 0.79 | PTAFR (0.34) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | claimed |
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | disclosed |
| US-5446032-A | Platelet activsating factor antagonist | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-08-29 | — | — | US | disclosed |
| EP-0605434-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993002080-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |