Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563759 | 0.93 | PTAFR (0.35) | BMP1KEAP1ALDH1A1PTAFR | |
| SCHEMBL8562710 | 0.92 | PTAFR (0.38) | BMP1TSHRSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8570931 | 0.91 | BMP1 (0.31) | BMP1 | |
| SCHEMBL8565325 | 0.87 | PTAFR (0.38) | ALDH1A1PTAFR | |
| SCHEMBL8569673 | 0.85 | PTAFR (0.38) | ALDH1A1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8562738 | 0.84 | PTAFR (0.36) | BMP1KEAP1ALDH1A1NFE2L2PTAFR | |
| SCHEMBL8561445 | 0.83 | PTAFR (0.36) | PTAFR | |
| SCHEMBL8565735 | 0.80 | PTAFR (0.39) | ALDH1A1PTAFR | |
| SCHEMBL8561481 | 0.80 | PTAFR (0.49) | SMN1; SMN2ALDH1A1NPSR1PTAFR | |
| SCHEMBL8565372 | 0.78 | PTAFR (0.41) | ALDH1A1MMP2MMP13PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | claimed |