Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565325 | 0.94 | PTAFR (0.38) | PTAFRPOLBALDH1A1TP53 | |
| SCHEMBL8570381 | 0.93 | BMP1 (0.34) | PTAFRALDH1A1BMP1KEAP1 | |
| SCHEMBL8570931 | 0.91 | BMP1 (0.31) | BMP1 | |
| SCHEMBL8562710 | 0.90 | PTAFR (0.38) | PTAFRPOLBALDH1A1BMP1 | |
| SCHEMBL8562738 | 0.89 | PTAFR (0.36) | PTAFRPOLBALDH1A1BMP1TP53 | |
| SCHEMBL8561445 | 0.88 | PTAFR (0.36) | PTAFR | |
| SCHEMBL8569673 | 0.85 | PTAFR (0.38) | PTAFRALDH1A1 | |
| SCHEMBL8565735 | 0.84 | PTAFR (0.39) | PTAFRPOLBALDH1A1TP53 | |
| SCHEMBL8561481 | 0.84 | PTAFR (0.49) | PTAFRPOLBALDH1A1TP53 | |
| SCHEMBL8567796 | 0.82 | PTAFR (0.38) | PTAFRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605434-B1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARM (GB) | 1998-08-19 | — | — | EP | claimed |