Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122649 | 0.81 | KMT2A (0.58) | CYP2A6CNR2KMT2ARAB9AMAPK1 | |
| Hydrochloric Acid SCHEMBL3062533 | 0.80 | KMT2A (0.57) | CNR2KMT2ARAB9AMAPK1KDM4E | |
| SCHEMBL19134389 | 0.79 | CYP2A6 (0.47) | CYP2A6CNR2KMT2ARAB9AALDH1A1 | |
| SCHEMBL13409643 | 0.79 | L3MBTL1 (0.33) | CYP2A6KMT2AMAPK1KDM4EL3MBTL1 | |
| SCHEMBL8250524 | 0.76 | CYP2A6 (0.52) | CYP2A6CNR2KMT2ARAB9AMAPK1 | |
| SCHEMBL16505189 | 0.76 | KDM4E (0.40) | KMT2AMAPK1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL23598620 | 0.75 | CNR2 (0.46) | CYP2A6CNR2RAB9APLAUF12 | |
| SCHEMBL11609998 | 0.75 | CNR2 (0.43) | CYP2A6CNR2KMT2ARAB9AMAPK1 | |
| SCHEMBL12438889 | 0.74 | RAB9A (0.49) | CYP2A6CNR2KMT2ARAB9AMAPK1 | |
| SCHEMBL31409876 | 0.74 | ALDH1A1 (0.39) | KMT2AMAPK1KDM4EALDH1A1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664795-B1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LTD (GB) | 1998-07-01 | — | — | EP | disclosed |
| US-5723473-A | Propenoic acid derivatives useful as fungicides | ZENECA LIMITED (GB) | 1998-03-03 | — | — | US | disclosed |
| EP-0664795-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008968-A1 | PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-04-28 | — | — | WO | disclosed |