Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 17/20 | 1.00 |
| ▸ | JUN | P05412 | 11/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 11/20 | 1.00 |
| ▸ | RELA | Q04206 | 11/20 | 1.00 |
| ▸ | ATF1 | P18846 | 7/20 | 0.79 |
| ▸ | XPO1 | O14980 | 5/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458841 | 0.88 | NFKB1 (1.00) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL8544541 | 0.81 | JUN (0.67) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL20558428 | 0.79 | NFKB1 (0.65) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL30421262 | 0.76 | NFKB1 (0.61) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL28557381 | 0.76 | NFKB1 (0.61) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL1864557 | 0.76 | NFKB1 (0.78) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL330789 | 0.76 | P2RX1 (0.64) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL13919647 | 0.76 | XPO1 (0.68) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL8566786 | 0.75 | JUN (0.64) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL22145723 | 0.74 | BRAF (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811428-A | ADMINISTERING FOR THE TREATMENT AND PREVENTION OF IMMUNOINFLAMMATORY AND AUTOIMMUNE DISEASES | SIGNAL PHARMACEUTICALS, INC. (US) | 1998-09-22 | — | — | US | disclosed |