Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 11/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 11/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 11/20 | 0.64 |
| ▸ | RELA | Q04206 | 11/20 | 0.64 |
| ▸ | XPO1 | O14980 | 3/20 | 0.64 |
| ▸ | ATF1 | P18846 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MYLK | Q15746 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24574900 | 0.76 | P2RX1 (0.59) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL8561758 | 0.75 | NFKB1 (1.00) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL12189407 | 0.71 | TLR7 (0.57) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL26786131 | 0.70 | JUN (0.59) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL17448400 | 0.70 | P2RX1 (0.63) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL14885884 | 0.69 | P2RX1 (0.66) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL458841 | 0.68 | NFKB1 (1.00) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL12172968 | 0.68 | TLR7 (0.48) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL30554609 | 0.68 | P2RX1 (0.51) | JUNNFKB1NFKB2RELAXPO1 | |
| SCHEMBL3241964 | 0.68 | P2RX1 (0.51) | JUNNFKB1NFKB2RELAXPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811428-A | ADMINISTERING FOR THE TREATMENT AND PREVENTION OF IMMUNOINFLAMMATORY AND AUTOIMMUNE DISEASES | SIGNAL PHARMACEUTICALS, INC. (US) | 1998-09-22 | — | — | US | claimed |