SCHEMBL8562260

SCHEMBL8562260

C=COC(=O)c1ccccc1-c1cccc2c1C(S(=O)(=O)c1ccccc1)=CCC2(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8563082 0.80 PDK2 (0.31)
SCHEMBL8561897 0.74 RARA (0.40)
SCHEMBL8165227 0.71 HTR2A (0.36)
SCHEMBL6292880 0.70 RARA (0.49)
SCHEMBL19506917 0.69 CYP3A4 (0.46)
SCHEMBL8644020 0.67 RARA (0.37)
SCHEMBL1901065 0.64 BCAT2 (0.52)
SCHEMBL1899053 0.62 NR4A1 (0.43)
Acetic Acid SCHEMBL27451410 0.62 CYP3A4 (0.48)
SCHEMBL1900622 0.61 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808124-A BINDING TO RETINOID RECEPTORS ALLERGAN (US) 1998-09-15 US disclosed