Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.51 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558577 | 0.94 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL8561230 | 0.90 | AVPR1A (0.46) | AVPR2AVPR1A | |
| SCHEMBL8559901 | 0.89 | AVPR2 (0.63) | AVPR2AVPR1AOXTR | |
| SCHEMBL8557927 | 0.89 | AVPR2 (0.51) | AVPR2AVPR1AOXTR | |
| SCHEMBL8559861 | 0.88 | AURKA (0.47) | AVPR2AVPR1A | |
| SCHEMBL8556991 | 0.87 | AVPR2 (0.58) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558202 | 0.85 | HTR1F (0.51) | AVPR2AVPR1AOXTR | |
| SCHEMBL8556942 | 0.85 | NPC1 (0.49) | — | |
| SCHEMBL8557883 | 0.85 | MEN1 (0.50) | AVPR2AVPR1A | |
| SCHEMBL8557390 | 0.85 | AVPR2 (0.52) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |