Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557390 | 0.91 | AVPR2 (0.52) | AVPR1AAVPR2 | |
| SCHEMBL8561230 | 0.90 | AVPR1A (0.46) | AVPR1AAVPR2LMNATP53MAPT | |
| SCHEMBL8560617 | 0.88 | AVPR1A (0.49) | TDP1AVPR1AAVPR2LMNARAB9A | |
| SCHEMBL8559901 | 0.88 | AVPR2 (0.63) | AVPR1AAVPR2 | |
| SCHEMBL8562449 | 0.87 | AVPR2 (0.46) | AVPR1AAVPR2LMNATP53 | |
| SCHEMBL8557851 | 0.87 | MAPT (0.48) | MEN1KMT2AAVPR1AAVPR2LMNA | |
| SCHEMBL8559885 | 0.86 | AVPR2 (0.46) | AVPR1AAVPR2 | |
| SCHEMBL8561948 | 0.85 | AVPR2 (0.51) | AVPR1AAVPR2 | |
| SCHEMBL8560629 | 0.85 | SMN1; SMN2 (0.51) | MEN1KMT2AAVPR1AAVPR2NPC1 | |
| SCHEMBL8557610 | 0.85 | MAPT (0.52) | KMT2AAVPR1AAVPR2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |