Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558577 | 0.91 | AVPR2 (0.57) | AVPR1AAVPR2 | |
| SCHEMBL8557883 | 0.90 | MEN1 (0.50) | AVPR1AAVPR2MAPTTP53LMNA | |
| SCHEMBL8561948 | 0.90 | AVPR2 (0.51) | AVPR1AAVPR2 | |
| SCHEMBL8557851 | 0.89 | MAPT (0.48) | AVPR1AAVPR2MAPTPOLBTP53 | |
| SCHEMBL8559861 | 0.87 | AURKA (0.47) | AVPR1AAVPR2 | |
| SCHEMBL8556942 | 0.86 | NPC1 (0.49) | MAPTTP53 | |
| SCHEMBL8557390 | 0.84 | AVPR2 (0.52) | AVPR1AAVPR2 | |
| SCHEMBL8558194 | 0.83 | AKT1 (0.52) | MAPTTP53LMNA | |
| SCHEMBL8563496 | 0.83 | AVPR2 (0.56) | AVPR1AAVPR2MAPT | |
| SCHEMBL8558117 | 0.83 | AVPR2 (0.47) | AVPR1AAVPR2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |