Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.42 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666651 | 0.89 | GLA (0.60) | KMT2AMAPTLMNAGLANPSR1 | |
| SCHEMBL8559225 | 0.85 | MAPT (0.54) | KMT2AMAPTLMNAGLANPSR1 | |
| SCHEMBL6976661 | 0.78 | NPC1 (0.54) | KMT2AMAPTTDP1LMNAGLA | |
| SCHEMBL7663124 | 0.75 | RAB9A (0.52) | KMT2AMAPTTDP1LMNANPSR1 | |
| SCHEMBL10962466 | 0.75 | GLA (0.81) | KMT2AMAPTLMNAGLANPSR1 | |
| SCHEMBL10962462 | 0.75 | GLA (0.81) | KMT2AMAPTLMNAGLANPSR1 | |
| SCHEMBL10962452 | 0.75 | GLA (0.81) | KMT2AMAPTLMNAGLANPSR1 | |
| SCHEMBL7670436 | 0.75 | KMT2A (0.39) | KMT2AMAPTTDP1GLANPSR1 | |
| SCHEMBL7659466 | 0.75 | CES1 (0.39) | KMT2AMAPTTDP1GLANPSR1 | |
| SCHEMBL7660280 | 0.74 | MCL1 (0.46) | KMT2AMAPTLMNAGLANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |