Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962462 | 1.00 | GLA (0.81) | GLANPSR1MCL1NPC1RAB9A | |
| SCHEMBL10962466 | 1.00 | GLA (0.81) | GLANPSR1MCL1NPC1RAB9A | |
| SCHEMBL7666651 | 0.85 | GLA (0.60) | GLANPSR1NPC1RAB9AAKR1C1 | |
| SCHEMBL5157487 | 0.81 | LMNA (0.57) | GLANPSR1MCL1NPC1RAB9A | |
| SCHEMBL27782319 | 0.81 | NPSR1 (0.56) | GLANPSR1MCL1NPC1RAB9A | |
| SCHEMBL10618678 | 0.77 | AKR1C1 (0.52) | GLANPSR1NPC1RAB9AAKR1C1 | |
| SCHEMBL22279105 | 0.76 | GLA (0.50) | GLANPSR1NPC1RAB9AAKR1C1 | |
| SCHEMBL8562016 | 0.75 | KMT2A (0.51) | GLANPSR1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL1942388 | 0.74 | MAPT (0.57) | NPC1RAB9AAKR1C1ALDH1A1KMT2A | |
| SCHEMBL7112204 | 0.74 | MAPT (0.57) | NPC1RAB9AAKR1C1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515731-A | Asymmetric catalysis | MONSANTO COMPANY (US) | 1985-05-07 | — | — | US | claimed |
| US-4515731-A | Asymmetric catalysis | MONSANTO COMPANY (US) | 1985-05-07 | — | — | US | disclosed |