Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666651 | 0.85 | GLA (0.60) | MAPTKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8562016 | 0.85 | KMT2A (0.51) | MAPTKMT2ACYP2C9ALDH1A1CYP2C19 | |
| SCHEMBL29011921 | 0.77 | GAA (0.71) | KMT2ANPC1RAB9ACYP2C9ALDH1A1 | |
| SCHEMBL27501942 | 0.77 | CYP11B2 (0.54) | MAPTKMT2ANPC1RAB9ACYP2C9 | |
| SCHEMBL2000041 | 0.75 | HDAC1 (0.74) | MAPTCYP2C9ALDH1A1GAAALPL | |
| SCHEMBL8559227 | 0.75 | ALDH1A1 (0.78) | MAPTKMT2ANPC1RAB9ACYP2C9 | |
| SCHEMBL6976661 | 0.75 | NPC1 (0.54) | MAPTKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5793445 | 0.74 | HDAC1 (0.67) | KMT2ANPC1RAB9ACYP2C9ALDH1A1 | |
| SCHEMBL10660987 | 0.72 | GAA (0.71) | KMT2AALDH1A1GAAALPLALPI | |
| SCHEMBL10660983 | 0.72 | GAA (0.71) | KMT2AALDH1A1GAAALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |