Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MGMT | P16455 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566816 | 0.84 | MAPT (0.43) | MAPTMGMTLMNAHPGDTLR8 | |
| SCHEMBL27196616 | 0.81 | MAPT (0.49) | MAPTMGMTLMNAHPGDMAPK1 | |
| SCHEMBL8559235 | 0.81 | KDM4E (0.41) | MAPTLMNAHPGDTLR8MAPK1 | |
| SCHEMBL8599452 | 0.81 | MAPT (0.43) | MAPTMGMTLMNAHPGDTLR8 | |
| SCHEMBL15147641 | 0.80 | TLR8 (0.51) | MAPTLMNAHPGDTLR8HTT | |
| SCHEMBL8567950 | 0.80 | CYP3A4 (0.47) | MAPTMGMTLMNAHPGDMAPK1 | |
| SCHEMBL8564398 | 0.79 | POLB (0.43) | MAPTMGMTLMNAHPGDTLR8 | |
| SCHEMBL27842115 | 0.79 | TLR8 (0.45) | MAPTMGMTLMNATLR8HTT | |
| SCHEMBL8596689 | 0.79 | TLR8 (0.61) | MAPTLMNAHPGDTLR8ALDH1A1 | |
| SCHEMBL3953291 | 0.79 | KDM4E (0.52) | MAPTMGMTLMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |