Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MGMT | P16455 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562265 | 0.84 | MAPT (0.48) | MAPTMGMTMAPK1LMNAHPGD | |
| SCHEMBL8599452 | 0.82 | MAPT (0.43) | MAPTMGMTCYP3A4MAPK1LMNA | |
| SCHEMBL8567950 | 0.81 | CYP3A4 (0.47) | MAPTMGMTCYP3A4MAPK1LMNA | |
| SCHEMBL12518927 | 0.80 | MAOA (0.48) | MAPTMGMTCYP3A4MAPK1LMNA | |
| SCHEMBL27842115 | 0.80 | TLR8 (0.45) | MAPTMGMTLMNAKMT2AHTT | |
| SCHEMBL8596689 | 0.80 | TLR8 (0.61) | MAPTLMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8564398 | 0.80 | POLB (0.43) | MAPTMGMTMAPK1LMNAHPGD | |
| SCHEMBL3953291 | 0.80 | KDM4E (0.52) | MAPTMGMTCYP3A4MAPK1LMNA | |
| SCHEMBL8566788 | 0.79 | KDM4E (0.41) | MAPTMAPK1LMNAHPGDKMT2A | |
| SCHEMBL10589352 | 0.78 | MEN1 (0.45) | MAPTMGMTCYP3A4MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |