Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MGMT | P16455 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559919 | 0.82 | POLB (0.43) | POLBMAPTALDH1A1EGFRTLR8 | |
| SCHEMBL8596689 | 0.82 | TLR8 (0.61) | MAPTALDH1A1TLR8LMNAHPGD | |
| SCHEMBL8562740 | 0.81 | MGMT (0.43) | POLBMGMTMAPTALDH1A1EGFR | |
| SCHEMBL8566816 | 0.80 | MAPT (0.43) | POLBMGMTMAPTALDH1A1TLR8 | |
| SCHEMBL27842115 | 0.80 | TLR8 (0.45) | POLBMGMTMAPTALDH1A1TLR8 | |
| SCHEMBL8566973 | 0.80 | POLB (0.43) | POLBMGMTMAPTALDH1A1EGFR | |
| SCHEMBL8562265 | 0.79 | MAPT (0.48) | POLBMGMTMAPTALDH1A1TLR8 | |
| SCHEMBL8599452 | 0.76 | MAPT (0.43) | POLBMGMTMAPTALDH1A1TLR8 | |
| SCHEMBL8567950 | 0.76 | CYP3A4 (0.47) | POLBMGMTMAPTALDH1A1LMNA | |
| SCHEMBL3953291 | 0.74 | KDM4E (0.52) | POLBMGMTMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |