Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | CLPP | Q16740 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17984953 | 0.84 | SLC6A5 (0.54) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| SCHEMBL16264682 | 0.84 | SLC6A5 (0.54) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| SCHEMBL9256480 | 0.83 | HPGD (0.51) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| Hydrochloric Acid SCHEMBL4793706 | 0.82 | HPGD (0.50) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| SCHEMBL16264683 | 0.81 | SLC6A5 (0.49) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| SCHEMBL31376614 | 0.81 | MEN1 (0.50) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| SCHEMBL8566026 | 0.81 | SLC6A5 (0.54) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| SCHEMBL8564321 | 0.80 | SLC6A5 (0.53) | SLC6A5ACHEAKR1B1KMT2AKDM4E | |
| SCHEMBL8560032 | 0.79 | SLC6A5 (0.47) | SLC6A5ACHEAKR1B1KDRMEN1 | |
| SCHEMBL8561824 | 0.79 | SLC6A5 (0.47) | SLC6A5ACHEAKR1B1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588500-B1 | 3-Oxadiazolyl-1,6-naphthyridine derivatives with affinity for benzodiazepine receptors | DAINIPPON PHARMACEUTICAL CO (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5424433-A | Benzodiazepine receptor agonist | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5424434-A | Intramolecular cyclodehydration with a phosphorus(III) compound and a dialkyl azodicarboxylate in presence of a base to form a benzodiazepine receptor agonist, anxiolytic agent | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5367078-A | Benzodiazine receptor agonists | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1994-11-22 | — | — | US | disclosed |
| EP-0588500-A2 | 3-Oxadiazolyl-1,6-naphthyridine derivatives with affinity for benzodiazepine receptors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |