Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567066 | 0.90 | MAPT (0.40) | STK4NPSR1SMN1; SMN2POLBMAPT | |
| SCHEMBL8563378 | 0.85 | PDE4B (0.59) | PDE4BCSF1RNPSR1SMN1; SMN2MAPT | |
| SCHEMBL8566689 | 0.85 | PDE4B (0.43) | STK4PDE4BCSF1RNPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL811230 | 0.85 | PDE4B (0.58) | PDE4BCSF1RNPSR1SMN1; SMN2MAPT | |
| SCHEMBL8564146 | 0.84 | CSF1R (0.50) | STK4PDE4BCSF1RNPSR1SMN1; SMN2 | |
| SCHEMBL8561356 | 0.84 | PDE4B (0.44) | STK4PDE4BCSF1RNPSR1SMN1; SMN2 | |
| SCHEMBL8565303 | 0.83 | CSF1R (0.62) | PDE4BCSF1R | |
| SCHEMBL8559490 | 0.83 | CSF1R (0.48) | PDE4BCSF1R | |
| SCHEMBL8563461 | 0.82 | PDE4B (0.41) | STK4PDE4BCSF1RNPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8565607 | 0.82 | CSF1R (0.48) | PDE4BCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | claimed |