Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MGMT | P16455 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565267 | 0.81 | MEN1 (0.50) | MEN1KMT2AGSTP1GSTM2LMNA | |
| SCHEMBL9909776 | 0.78 | LMNA (0.61) | HTTGSTP1GSTM2LMNAALDH1A1 | |
| SCHEMBL22531432 | 0.78 | POLB (0.62) | MEN1KMT2AHTTGSTP1GSTM2 | |
| SCHEMBL8567672 | 0.78 | MEN1 (0.60) | MEN1KMT2AHTTGSTP1GSTM2 | |
| SCHEMBL18708571 | 0.76 | GSTP1 (0.52) | MEN1KMT2AGSTP1GSTM2LMNA | |
| SCHEMBL8596783 | 0.76 | HTT (0.40) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL8568481 | 0.75 | HTT (0.50) | MEN1KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL8568938 | 0.75 | GSTP1 (0.49) | MEN1KMT2AHTTGSTP1GSTM2 | |
| SCHEMBL8595691 | 0.74 | GPR84 (0.44) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL5036374 | 0.73 | MGMT (0.58) | MEN1KMT2AHTTLMNAMGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |