Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MGMT | P16455 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954517 | 0.82 | CYP19A1 (0.41) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL28238100 | 0.81 | HTT (0.49) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL4954513 | 0.81 | MEN1 (0.46) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL1699180 | 0.79 | LMNA (0.44) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL5145767 | 0.79 | MAPT (0.47) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL8566712 | 0.79 | CYP19A1 (0.43) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL9995175 | 0.78 | HTT (0.42) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL8598075 | 0.78 | HTT (0.42) | HTTLMNAMGMTMAPTSMN1; SMN2 | |
| SCHEMBL5036374 | 0.77 | MGMT (0.58) | HTTLMNAMGMTMAPTCYP19A1 | |
| SCHEMBL3476385 | 0.76 | HTR2A (0.41) | HTTLMNAMGMTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |