Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561595 | 0.91 | ACHE (0.61) | ACHEAVPR1AAVPR2 | |
| SCHEMBL8557374 | 0.89 | AVPR2 (0.58) | ACHEAVPR1AAVPR2 | |
| SCHEMBL8561780 | 0.88 | AVPR2 (0.54) | ACHEAVPR1AAVPR2 | |
| SCHEMBL8561962 | 0.88 | AVPR2 (0.58) | ACHEAVPR1AAVPR2 | |
| SCHEMBL8563728 | 0.86 | AVPR2 (0.55) | ACHEAVPR1AAVPR2RAB9A | |
| SCHEMBL8560236 | 0.85 | MEN1 (0.48) | ACHEAVPR1AAVPR2KDM4E | |
| SCHEMBL8557743 | 0.84 | AVPR2 (0.64) | ACHEAVPR1AAVPR2 | |
| SCHEMBL8562554 | 0.82 | AVPR2 (0.73) | AVPR1AAVPR2 | |
| SCHEMBL8559571 | 0.82 | AVPR2 (0.62) | AVPR1AAVPR2 | |
| SCHEMBL8556841 | 0.82 | AVPR2 (0.65) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |