Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557374 | 0.95 | AVPR2 (0.58) | AVPR2AVPR1AACHE | |
| SCHEMBL8561595 | 0.91 | ACHE (0.61) | AVPR2AVPR1AACHE | |
| SCHEMBL8557743 | 0.90 | AVPR2 (0.64) | AVPR2AVPR1AACHE | |
| SCHEMBL8562909 | 0.86 | ACHE (0.52) | AVPR2AVPR1AACHERAB9A | |
| SCHEMBL8562554 | 0.85 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL8559508 | 0.83 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8556841 | 0.83 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8559571 | 0.83 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL8558900 | 0.82 | AVPR2 (0.65) | AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL8559877 | 0.82 | AVPR2 (0.53) | AVPR2AVPR1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |