Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561506 | 0.81 | PIK3CD (0.35) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL21672318 | 0.76 | PGK1 (0.45) | CA1CA2CA9PTK2KMT2A | |
| SCHEMBL30456319 | 0.76 | ALDH1A1 (0.46) | CA1CA2CA9PTK2KMT2A | |
| SCHEMBL18130725 | 0.74 | NPC1 (0.47) | PTK2KDM4EHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL25604920 | 0.74 | ALDH1A1 (0.43) | PTK2KMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL9261109 | 0.73 | KMT2A (0.41) | CA1CA2CA9PTK2KMT2A | |
| Acetic Acid SCHEMBL28092089 | 0.73 | ALDH1A1 (0.44) | CA1CA2CA9PTK2KMT2A | |
| SCHEMBL16441504 | 0.73 | PTK2 (0.41) | CA1CA2CA9PTK2KMT2A | |
| SCHEMBL17059904 | 0.68 | MEN1 (0.44) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL11816879 | 0.65 | TRPV1 (0.50) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618209-B1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-12-23 | — | — | EP | disclosed |
| EP-0618209-A1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-10-05 | — | — | EP | disclosed |