Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562984 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1HPGDPKM | |
| SCHEMBL27554758 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1HPGDPKM | |
| SCHEMBL8561177 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HPGDGAA | |
| SCHEMBL8561171 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HPGDGAA | |
| SCHEMBL16885994 | 0.84 | KMT2A (0.54) | ALDH1A1KMT2AMEN1HPGDPKM | |
| SCHEMBL11735404 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1HPGDPKM | |
| SCHEMBL1543096 | 0.81 | MEN1 (0.54) | ALDH1A1KMT2AMEN1HPGDGAA | |
| SCHEMBL8562678 | 0.81 | HPGD (0.49) | ALDH1A1KMT2AHPGDGAANPC1 | |
| SCHEMBL8562675 | 0.81 | HPGD (0.49) | ALDH1A1KMT2AHPGDGAANPC1 | |
| SCHEMBL8568656 | 0.80 | MMP8 (0.51) | ALDH1A1KMT2AMEN1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |