SCHEMBL8563087

SCHEMBL8563087

c1ccc2c(c1)ccc1ccoc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
CYP2A6 P11509 4/20 0.50
HSD17B10 Q99714 3/20 0.50
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
HPRT1 P00492 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CYP1B1 Q16678 5/20 0.42
HIF1A Q16665 1/20 0.42
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41
ESR1 P03372 1/20 0.41
HTT P42858 1/20 0.41
CYP1A2 P05177 5/20 0.41
CYP1A1 P04798 4/20 0.41
ABCG2 Q9UNQ0 2/20 0.41
PDE5A O76074 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853219 1.00 ALDH1A1 (0.50) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL29837225 0.89 HPRT1 (0.58) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL15511404 0.89 HPRT1 (0.58) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL31011152 0.89 HPRT1 (0.58) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL20873440 0.89 HPRT1 (0.58) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL4111060 0.86 ALDH1A1 (0.45) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL18740448 0.85 HSD17B10 (0.44) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL28975020 0.84 CYP1A2 (0.43) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL14358959 0.80 MAOA (0.46) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL29265552 0.80 HPRT1 (0.52) ALDH1A1CYP2A6HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230373929-A1 FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF XIANGBEI WELMAN PHARMACEUTICAL CO., LTD. (CN) 2023-11-23 US claimed
EP-4215521-A1 FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF Xiangbei Welman Pharmaceutical Co., Ltd (CN) 2023-07-26 EP claimed
US-20220259493-A1 SOLAR WAVELENGTH CONVERSION MATERIAL, SOLAR CELL ENCAPSULANT COMPRISING SAME, AND SOLAR CELL COMPRISING SAME HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2022-08-18 US claimed
WO-2022073445-A1 FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 广州新创意生物医药有限公司 2022-04-14 WO claimed
CN-103764140-B Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical compositions containing same as active ingredient for preventing or treating viral diseases 韩国化学研究院 2017-05-17 CN claimed
CN-1168725-A Novel photochromic indeno fused naphthopyrans PPG INDUSTRIES INC (US) 1997-12-24 CN claimed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-06-12 US disclosed
US-11829036-B2 Optically anisotropic multilayer product and method for producing same ZEON CORPORATION (JP) 2023-11-28 US disclosed
CN-117119865-A Light emitting element, electronic device including the same, and electronic apparatus including the same 三星显示有限公司 2023-11-24 CN disclosed
US-20230373929-A1 FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF XIANGBEI WELMAN PHARMACEUTICAL CO., LTD. (CN) 2023-11-23 US disclosed
EP-3668948-B1 POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2023-10-25 EP disclosed
EP-3668947-B1 POLYMERISABLE LC MEDIUM AND POLYMER FILM WITH FLAT OPTICAL DISPERSION MERCK PATENT GMBH (DE) 2023-09-27 EP disclosed
US-20120129105-A1 PHOTOSENSITIVE COPOLYMER AND PHOTORESIST COMPOSITION ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-05-24 US disclosed
US-20120129105-A1 PHOTOSENSITIVE COPOLYMER AND PHOTORESIST COMPOSITION ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-05-24 US disclosed
EP-2455812-A2 Photosensitive copolymer and photoresist composition Rohm and Haas Electronic Materials LLC (US) 2012-05-23 EP disclosed
CN-102448945-A Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO 2012-05-09 CN disclosed
CN-1168725-A Novel photochromic indeno fused naphthopyrans PPG INDUSTRIES INC (US) 1997-12-24 CN disclosed
US-5244917-A Antiallergens THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1993-09-14 US disclosed
US-4470990-A 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants AYERST, MCKENNA & HARRISON INC. (CA) 1984-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB ALDH1A1 2667/4885CYP2A6 1256/4885HSD17B10 1149/4885
US-20230373929-A1 FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF WEE1, CYP51A1, WEE2 ALDH1A1 612/4885CYP2A6 1574/4885HSD17B10 1243/4885
US-20250186391-A1 ORAL COMPLEMENT FACTOR D INHIBITORS CFD, CFH, CFB ALDH1A1 3142/4885CYP2A6 1436/4885HSD17B10 2891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.