Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801633 | 0.98 | HSP90AB1 (0.58) | HSP90AB1ALDH1A1GAAGFERPTGS1 | |
| SCHEMBL21620954 | 0.89 | ALDH1A1 (0.61) | HSP90AB1ALDH1A1GAAGFERPTGS1 | |
| Methane SCHEMBL10411744 | 0.84 | MAOB (0.50) | ALDH1A1PTGS1AKR1C3AKR1C2ALOX5 | |
| Methane SCHEMBL9087821 | 0.83 | PTGS1 (0.71) | HSP90AB1ALDH1A1GAAGFERPTGS1 | |
| SCHEMBL2662328 | 0.83 | MEN1 (0.57) | ALDH1A1GAAGFERPTGS1AKR1C3 | |
| SCHEMBL31170867 | 0.83 | MEN1 (0.57) | ALDH1A1GAAGFERPTGS1AKR1C3 | |
| SCHEMBL12419939 | 0.83 | ALDH1A1 (0.54) | HSP90AB1ALDH1A1GAAGFERPTGS1 | |
| SCHEMBL21451484 | 0.83 | CYP11B1 (0.59) | HSP90AB1ALDH1A1GAAGFERPTGS1 | |
| SCHEMBL10411098 | 0.82 | MAOB (0.51) | ALDH1A1PTGS1AKR1C3AKR1C2ALOX5 | |
| SCHEMBL4548368 | 0.82 | LMNA (0.53) | ALDH1A1ALOX5MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882057-A1 | SIALYL LEWIS X MIMETICS CONTAINING NAPHTHYL BACKBONES | GLYCOMED INCORPORATED (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5837689-A | TREATING A SELECTIN-MEDIATED DISORDER SUCH AS CANCER, AUTOIMMUNE DISEASES, INFLAMMATION | GLYCOMED INCORPORATED (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1997031006-A1 | SIALYL LEWISx MIMETICS CONTAINING NAPHTHYL BACKBONES | GLYCOMED INCORPORATED (US) | 1997-08-28 | — | — | WO | disclosed |
| US-4937373-A | Substituted naphthalene carboxylic acids | HOFFMANN-LA ROCHE INC. (US) | 1990-06-26 | — | — | US | disclosed |