SCHEMBL7801633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Methane SCHEMBL8563134	0.98	HSP90AB1 (0.56)	HSP90AB1ALDH1A1GAAGFERPTGS1
	SCHEMBL21620954	0.91	ALDH1A1 (0.61)	HSP90AB1ALDH1A1GAAGFERPTGS1
	SCHEMBL2662328	0.84	MEN1 (0.57)	ALDH1A1GAAGFERPTGS1AKR1C3
	SCHEMBL31170867	0.84	MEN1 (0.57)	ALDH1A1GAAGFERPTGS1AKR1C3
	SCHEMBL21451484	0.84	CYP11B1 (0.59)	HSP90AB1ALDH1A1GAAGFERPTGS1
	SCHEMBL12419939	0.84	ALDH1A1 (0.54)	HSP90AB1ALDH1A1GAAGFERPTGS1
	SCHEMBL10411098	0.83	MAOB (0.51)	ALDH1A1PTGS1AKR1C3AKR1C2ALOX5
	SCHEMBL4548368	0.83	LMNA (0.53)	ALDH1A1ALOX5MAPTNPC1RAB9A
	SCHEMBL8935104	0.83	ALDH1A1 (0.53)	HSP90AB1ALDH1A1GAAGFERPTGS1
	SCHEMBL1448732	0.83	PTGS1 (0.73)	HSP90AB1ALDH1A1GAAGFERPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.