Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 13/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601222 | 0.84 | MAPT (0.42) | NPC1RAB9ASMN1; SMN2S1PR4KMT2A | |
| SCHEMBL8566254 | 0.79 | IKBKB (0.42) | IKBKBNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8568292 | 0.79 | ALDH1A1 (0.39) | IKBKBNPC1RAB9ASMN1; SMN2S1PR4 | |
| SCHEMBL3142475 | 0.79 | S1PR4 (0.63) | NPC1RAB9AS1PR4KMT2ALMNA | |
| SCHEMBL5037080 | 0.76 | IKBKB (0.49) | IKBKBCCNT1CDK9CDK5CDK5R1 | |
| SCHEMBL8566190 | 0.75 | KMT2A (0.58) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL214555 | 0.75 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL24399163 | 0.73 | S1PR4 (0.41) | NPC1RAB9ASMN1; SMN2S1PR4KMT2A | |
| SCHEMBL5041183 | 0.73 | KMT2A (0.40) | IKBKBNPC1RAB9ASMN1; SMN2S1PR4 | |
| SCHEMBL29508235 | 0.73 | S1PR4 (0.41) | NPC1RAB9ASMN1; SMN2S1PR4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |