Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764478 | 0.84 | MEN1 (0.54) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL29871162 | 0.84 | MEN1 (0.54) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL8599059 | 0.84 | CYP19A1 (0.43) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL5041183 | 0.82 | KMT2A (0.40) | IKBKBSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8563136 | 0.79 | IKBKB (0.45) | IKBKBSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8565117 | 0.79 | MAPT (0.39) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL5038254 | 0.79 | CYP11B1 (0.50) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL23352311 | 0.78 | NPC1 (0.53) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL30681720 | 0.78 | NPC1 (0.46) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL27143261 | 0.78 | NPC1 (0.46) | SMN1; SMN2KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |