Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563136 | 0.84 | IKBKB (0.45) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL8628083 | 0.80 | CYP19A1 (0.37) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL8599059 | 0.80 | CYP19A1 (0.43) | MAPTSMN1; SMN2GAALMNANPC1 | |
| SCHEMBL8596386 | 0.79 | S1PR4 (0.58) | MAPTLMNANPC1RAB9AMEN1 | |
| SCHEMBL8599944 | 0.79 | ALDH1A1 (0.49) | MAPTGAALMNANPC1RAB9A | |
| SCHEMBL8600006 | 0.78 | HTT (0.36) | MAPTLMNANPC1RAB9AMEN1 | |
| SCHEMBL28003388 | 0.77 | BID (0.38) | MAPTSMN1; SMN2GAARAB9AMEN1 | |
| SCHEMBL28245348 | 0.77 | GABRP (0.38) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL248876 | 0.75 | NPC1 (0.53) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL8598700 | 0.75 | HCAR3 (0.44) | MAPTSMN1; SMN2ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |