Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MGMT | P16455 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567087 | 0.84 | VCAM1 (0.46) | MAPTLMNAMAPK1VCAM1NPY5R | |
| SCHEMBL8603376 | 0.83 | GSK3A (0.41) | MAPTLMNAMAPK1HPGDHTT | |
| SCHEMBL8561022 | 0.82 | MAPT (0.44) | MAPTLMNAMAPK1HPGDHTT | |
| SCHEMBL8568939 | 0.82 | VCAM1 (0.46) | MAPTLMNAMAPK1HPGDVCAM1 | |
| SCHEMBL8596066 | 0.81 | NPY5R (0.43) | MAPTLMNAMAPK1NPY5RHTT | |
| SCHEMBL8567025 | 0.80 | MAPT (0.43) | MAPTLMNAMAPK1HPGDHTT | |
| SCHEMBL8565650 | 0.80 | MGMT (0.50) | MAPTLMNAMAPK1HPGDHTT | |
| SCHEMBL8569382 | 0.79 | MAPT (0.39) | MAPTLMNAMAPK1HPGDHTT | |
| SCHEMBL8563517 | 0.79 | MAPT (0.61) | MAPTLMNAMAPK1HPGDHTT | |
| SCHEMBL8564800 | 0.78 | VCAM1 (0.53) | MAPTLMNAMAPK1VCAM1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |