Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567025 | 0.87 | MAPT (0.43) | MAPTMGMTCYP3A4KMT2AMEN1 | |
| SCHEMBL842583 | 0.84 | CYP3A4 (0.40) | MAPTCYP3A4KMT2AMEN1S100A4 | |
| SCHEMBL842584 | 0.84 | CYP3A4 (0.40) | MAPTCYP3A4KMT2AMEN1S100A4 | |
| SCHEMBL8561022 | 0.81 | MAPT (0.44) | MAPTMGMTCYP3A4KMT2APOLB | |
| SCHEMBL8566049 | 0.80 | KDM4E (0.40) | MAPTKMT2AMEN1S100A4POLB | |
| SCHEMBL8567950 | 0.80 | CYP3A4 (0.47) | MAPTMGMTCYP3A4KMT2AMEN1 | |
| SCHEMBL8601772 | 0.79 | MAPT (0.40) | MAPTMGMTCYP3A4KMT2AMEN1 | |
| SCHEMBL8563164 | 0.79 | MAPT (0.51) | MAPTMGMTPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL8567514 | 0.79 | S100A4 (0.54) | MAPTMGMTCYP3A4KMT2AMEN1 | |
| SCHEMBL3953291 | 0.79 | KDM4E (0.52) | MAPTMGMTCYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |