Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600372 | 0.82 | LMNA (0.48) | SMN1; SMN2LMNAALOX12ALDH1A1HTT | |
| SCHEMBL8563177 | 0.81 | TSHR (0.48) | POLBEGFRSMN1; SMN2LMNANCF1 | |
| SCHEMBL8567677 | 0.80 | KMT2A (0.50) | POLBEGFRSMN1; SMN2LMNAALOX12 | |
| SCHEMBL8564398 | 0.80 | POLB (0.43) | POLBEGFRLMNANCF1ALDH1A1 | |
| SCHEMBL8561208 | 0.79 | HPGD (0.43) | POLBSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL8559919 | 0.77 | POLB (0.43) | POLBEGFRSMN1; SMN2LMNAALOX12 | |
| SCHEMBL8598680 | 0.76 | MAPT (0.38) | POLBEGFRSMN1; SMN2LMNAALOX12 | |
| SCHEMBL8564063 | 0.76 | EGFR (0.39) | POLBEGFRSMN1; SMN2LMNANCF1 | |
| SCHEMBL8564067 | 0.76 | EGFR (0.39) | POLBEGFRSMN1; SMN2LMNANCF1 | |
| SCHEMBL8565807 | 0.75 | KDM4E (0.44) | POLBEGFRSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |