Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563188 | 1.00 | EPHX2 (0.42) | EPHX2MTNR1AMTNR1BMAPK1BRD4 | |
| SCHEMBL7424500 | 0.86 | EPHX2 (0.40) | EPHX2MTNR1AMTNR1BMAPK1MEN1 | |
| SCHEMBL881106 | 0.73 | MTNR1A (0.44) | EPHX2MTNR1AMTNR1BBRD4CREBBP | |
| SCHEMBL12610368 | 0.73 | MTNR1A (0.44) | EPHX2MTNR1AMTNR1BBRD4CREBBP | |
| SCHEMBL29332740 | 0.73 | MTNR1A (0.44) | EPHX2MTNR1AMTNR1BBRD4CREBBP | |
| SCHEMBL8562992 | 0.72 | EPHX2 (0.43) | EPHX2MTNR1AMTNR1BMAPK1BRD4 | |
| SCHEMBL8569787 | 0.71 | EPHX2 (0.42) | EPHX2MTNR1AMTNR1BMAPK1BRD4 | |
| SCHEMBL8569796 | 0.71 | EPHX2 (0.42) | EPHX2MTNR1AMTNR1BMAPK1BRD4 | |
| SCHEMBL8563906 | 0.67 | MTNR1A (0.44) | MTNR1AMTNR1BBRD4 | |
| SCHEMBL8563917 | 0.67 | MTNR1A (0.44) | MTNR1AMTNR1BBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |