Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.51 |
| ▸ | ITGAV | P06756 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563850 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7388130 | 0.82 | ITGB3 (0.52) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL8563218 | 0.80 | ITGB3 (0.44) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| SCHEMBL7395829 | 0.80 | ITGB3 (0.59) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7387031 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8558942 | 0.79 | S1PR1 (0.41) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7394699 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8562284 | 0.78 | HTR6 (0.40) | — | |
| Hydrochloric Acid SCHEMBL9409618 | 0.76 | ITGB3 (0.52) | ITGB3ITGA2BITGAVCHRM2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9409399 | 0.74 | ITGB3 (0.51) | ITGB3ITGA2BITGAVCHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0612741-A1 | Cyclic derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-08-31 | — | — | EP | disclosed |