Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 known ✓ | P25103 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6881465 | 0.81 | HTR6 (0.33) | HTR6HTR2ARET | |
| SCHEMBL8568582 | 0.79 | HTR2A (0.34) | HTR6HTR2ARET | |
| Hydrochloric Acid SCHEMBL8568820 | 0.79 | HTR2A (0.41) | HTR6HTR2ARET | |
| Ethylene SCHEMBL819410 | 0.76 | HTR2A (0.38) | HTR6HTR2A | |
| SCHEMBL6881475 | 0.75 | HTR6 (0.32) | HTR6HTR2A | |
| SCHEMBL8565035 | 0.75 | HTR2A (0.35) | HTR6HTR2A | |
| SCHEMBL4470027 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9459876 | 0.75 | HTR2A (0.36) | HTR6HTR2ARET | |
| Hydrochloric Acid SCHEMBL8568812 | 0.75 | HTR2A (0.36) | HTR6HTR2ARET | |
| Hydrochloric Acid SCHEMBL30216611 | 0.75 | HTR2A (0.36) | HTR6HTR2ARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830820-A | Olefin polymerization catalyst and olefin polymerization process | TOSOH CORPORATION (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0658576-B1 | Olefin polymerization catalyst and olefin polymerization process | TOSOH CORP (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0658576-A1 | Olefin polymerization catalyst and olefin polymerization process | Tosoh Corporation (JP) | 1995-06-21 | — | — | EP | disclosed |