SCHEMBL8568582

SCHEMBL8568582

[SiH3]OC(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34
HTR6 P50406 1/20 0.34
RET P07949 1/20 0.32
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6881465 0.79 HTR6 (0.33) HTR2AHTR6RET
Hydrochloric Acid SCHEMBL8563236 0.79 HTR6 (0.33) HTR2AHTR6RET
SCHEMBL8368203 0.78 HTR2A (0.38) HTR2AHTR6RETSIGMAR1
SCHEMBL8565035 0.77 HTR2A (0.35) HTR2AHTR6
SCHEMBL6881475 0.77 HTR6 (0.32) HTR2AHTR6
SCHEMBL4651453 0.75 HTR6 (0.41) HTR2AHTR6SIGMAR1
SCHEMBL9143881 0.74 HTR6 (0.40) HTR2AHTR6
SCHEMBL9146269 0.74 HTR6 (0.40) HTR2AHTR6
SCHEMBL9056494 0.74 HTR2A (0.38) HTR2AHTR6RETSIGMAR1
SCHEMBL668104 0.74 SIGMAR1 (0.38) HTR2AHTR6RETSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5795839-A COORDINATION POLYMERIZATION CATALYST FOR POLYOLEFIN MANUFACTURE NIPPON OIL CO., LTD. (JP) 1998-08-18 US disclosed
EP-0546690-B1 Catalyst components for polymerization of olefins NIPPON OIL CO LTD (JP) 1998-03-04 EP disclosed
US-5707914-A ZIRCONIUM OR HAFNIUM ALKYLS OR ALKOXIDES NIPPON OIL CO., LTD. (JP) 1998-01-13 US disclosed
US-5677401-A COORDINATION CATALYST NIPPON OIL CO., LTD. (JP) 1997-10-14 US disclosed
US-5625014-A Method for polymerization of olefins NIPPON OIL CO., LTD. (JP) 1997-04-29 US disclosed
US-5331071-A Transition metal and alumoxane components NIPPON OIL CO., LTD. (JP) 1994-07-19 US disclosed
EP-0546690-A1 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1993-06-16 EP disclosed