Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564951 | 0.81 | ALDH1A1 (0.34) | ALDH1A1HPGDALOX15MAPTMEN1 | |
| SCHEMBL8569645 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HPGDALOX15IDO1S1PR4 | |
| SCHEMBL8561264 | 0.75 | S1PR4 (0.39) | ALDH1A1HPGDS1PR4MAPTMEN1 | |
| SCHEMBL8568828 | 0.74 | TDP1 (0.48) | ALDH1A1HPGDALOX15POLBMAPT | |
| SCHEMBL8562235 | 0.74 | TDP1 (0.48) | ALDH1A1HPGDALOX15POLBMAPT | |
| SCHEMBL8568195 | 0.74 | KMT2A (0.36) | ALDH1A1S1PR4POLBPRKCQMAPT | |
| SCHEMBL8561747 | 0.74 | MAPT (0.37) | ALDH1A1HPGDALOX15POLBPRKCQ | |
| SCHEMBL8596671 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL29177457 | 0.74 | MBOAT4 (0.33) | IDO1MAPTKDM4EALOX5APFEN1 | |
| SCHEMBL2207272 | 0.73 | TDP1 (0.53) | ALDH1A1ALOX15POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |