Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562235 | 0.88 | TDP1 (0.48) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL30467812 | 0.83 | TDP1 (0.48) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL9367583 | 0.83 | TDP1 (0.48) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL8566803 | 0.82 | ALOX15 (0.44) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL28076647 | 0.80 | MAPT (0.45) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL5623763 | 0.80 | TSHR (0.52) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL8566378 | 0.80 | ALDH1A1 (0.36) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL9974734 | 0.80 | ALDH1A1 (0.46) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL12161520 | 0.80 | ALDH1A1 (0.46) | TDP1ALDH1A1ALOX15CYP3A4TSHR | |
| SCHEMBL8078061 | 0.77 | ALDH1A1 (0.53) | TDP1ALDH1A1ALOX15CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |