SCHEMBL8614474

SCHEMBL8614474

O=C(O)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
ACLY P53396 2/20 0.38
ALDH1A1 P00352 1/20 0.35
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
CA2 P00918 3/20 0.33
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
LMNA P02545 1/20 0.32
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3863734 1.00 THRB (0.48) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL3858790 1.00 THRB (0.48) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL8618188 1.00 THRB (0.48) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL3862118 1.00 THRB (0.48) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL8618888 1.00 THRB (0.48) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL3864225 1.00 THRB (0.48) THRBACLYALDH1A1HMGCRCHRM1
Ammonia Solution, Strong SCHEMBL27987372 0.98 THRB (0.46) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL3861185 0.97 THRB (0.44) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL8562549 0.92 ACLY (0.42) THRBACLYALDH1A1HMGCRCHRM1
SCHEMBL8563267 0.92 ACLY (0.42) THRBACLYALDH1A1HMGCRCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117783362-A Method for detecting content of perfluoro and polyfluoro compound 中国计量科学研究院 2024-03-29 CN claimed
CN-111682113-B Pyrocatechol anchoring molecule passivation perovskite solar cell containing long fluorocarbon chain and preparation method thereof 西北工业大学 2021-09-21 CN claimed
CN-111682113-A Pyrocatechol anchoring molecule passivation perovskite solar cell containing long fluorocarbon chain and preparation method thereof 西北工业大学 2020-09-18 CN claimed
US-20260023052-A1 METHOD FOR MEASURING CONCENTRATION OF PER- AND POLYFLUOROALKYL SUBSTANCE AND LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY SYSTEM RESEARCH CENTER FOR ECO-ENVIRONMENTAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) 2026-01-22 US disclosed
EP-4579235-A1 METHOD FOR DETERMINATION OF CONCENTRATIONS OF PER- AND POLYFLUOROALKYL SUBSTANCES, AND LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY SYSTEM Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences (CN) 2025-07-02 EP disclosed
CN-117783362-A Method for detecting content of perfluoro and polyfluoro compound 中国计量科学研究院 2024-03-29 CN disclosed
WO-2024041610-A1 METHOD FOR DETERMINATION OF CONCENTRATIONS OF PER- AND POLYFLUOROALKYL SUBSTANCES, AND LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY SYSTEM 中国科学院生态环境研究中心 2024-02-29 WO disclosed
US-11891313-B2 Fluidic impedance platform for in-situ detection and quantification of PFAS in groundwater BATTELLE MEMORIAL INSTITUTE (US) 2024-02-06 US disclosed
US-20230393068-A1 Systems and Methods Employing Carbon Dots for the Measurement of Per- And Poly-Fluoroalkyl Substances TRIAD GROWTH PARTNERS LLC (US) 2023-12-07 US disclosed
CN-116722225-A Lithium ion battery electrolyte containing fluoroester and application thereof 江西永兴特钢新能源科技有限公司 2023-09-08 CN disclosed
WO-2023122143-A1 METHODS AND COMPOSITIONS FOR PFAS DEFLUORINATION DETECTION GINKGO BIOWORKS, INC. (US) 2023-06-29 WO disclosed
US-20230089418-A1 COMPOSITION AND METHOD FOR CAPTURE AND DEGRADATION OF PFAS BATTELLE MEMORIAL INSTITUTE (US) 2023-03-23 US disclosed
US-11518689-B2 Composition and method for capture and degradation of PFAS BATTELLE MEMORIAL INSTITUTE (US) 2022-12-06 US disclosed
CN-111682113-B Pyrocatechol anchoring molecule passivation perovskite solar cell containing long fluorocarbon chain and preparation method thereof 西北工业大学 2021-09-21 CN disclosed
US-20200369536-A1 COMPOSITION AND METHOD FOR CAPTURE AND DEGRADATION OF PFAS BATTELLE MEMORIAL INSTITUTE (US) 2020-11-26 US disclosed
CN-111682113-A Pyrocatechol anchoring molecule passivation perovskite solar cell containing long fluorocarbon chain and preparation method thereof 西北工业大学 2020-09-18 CN disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260023052-A1 METHOD FOR MEASURING CONCENTRATION OF PER- AND POLYFLUOROALKYL SUBSTANCE AND LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY SYSTEM PFAS, SRMS, PHOSPHO1 THRB 3029/4885ACLY 1124/4885ALDH1A1 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.