Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8864540 | 0.99 | SMN1; SMN2 (0.78) | SMN1; SMN2TSHRUSP2NPSR1POLB | |
| SCHEMBL8565487 | 0.89 | SMN1; SMN2 (1.00) | SMN1; SMN2TSHRUSP2NPSR1POLB | |
| Bromide SCHEMBL8864660 | 0.88 | SMN1; SMN2 (0.97) | SMN1; SMN2TSHRUSP2NPSR1POLB | |
| SCHEMBL9568271 | 0.86 | SMN1; SMN2 (0.86) | SMN1; SMN2TSHRUSP2NPSR1POLB | |
| Bromide SCHEMBL8864504 | 0.85 | SMN1; SMN2 (0.84) | SMN1; SMN2TSHRUSP2NPSR1POLB | |
| SCHEMBL6325602 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2TSHRUSP2NPSR1POLB | |
| SCHEMBL29738297 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRUSP2NPSR1ALDH1A1 | |
| SCHEMBL19713871 | 0.72 | CYP1A2 (0.63) | SMN1; SMN2TSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL6321352 | 0.71 | NPSR1 (0.98) | SMN1; SMN2TSHRUSP2NPSR1POLB | |
| Bromide SCHEMBL1294356 | 0.71 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRUSP2NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5623073-A | ANTIDIABETIC AGENT | ADIR ET COMPAGNIE (FR) | 1997-04-22 | — | — | US | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |