SCHEMBL535647

SCHEMBL535647

Cc1csc(C(=O)O)c1N

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
POLB P06746 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.41
PKM P14618 2/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
GPR35 Q9HC97 4/20 0.40
DAO P14920 2/20 0.38
AXL P30530 1/20 0.35
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7034535 0.98 TDP1 (0.50) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL10472839 0.98 L3MBTL1 (0.50) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL27404772 0.88 POLB (0.42) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL28971360 0.86 ALDH1A1 (0.44) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL27430005 0.83 L3MBTL1 (0.40) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL14125042 0.83 KDM4E (0.41) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL3717041 0.83 IKBKB (0.41) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL15751449 0.78 POLB (0.35) L3MBTL1POLBTDP1GAA
SCHEMBL25467512 0.78 GAA (0.41) L3MBTL1POLBTDP1ALDH1A1KDM4E
SCHEMBL2062392 0.78 GAA (0.45) L3MBTL1POLBTDP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2556062-B1 AMIDE DERIVATIVES OF AVENALUMIC ACID, PROCESS FOR PREPARING SAME AND COSMETIC COMPOSITIONS CONTAINING SAME PROD CHIM AUXILIAIRES ET DE SYNTHESE (FR) 2017-01-04 EP claimed
EP-2906566-B1 PROCESS FOR MAKING THIENOPYRIMIDINE COMPOUNDS HOFFMANN LA ROCHE (CH) 2016-08-24 EP claimed
EP-2214675-B1 PROCESS FOR MAKING THIENOPYRIMIDINE COMPOUNDS GENENTECH INC (US) 2013-11-20 EP claimed
EP-2556062-A1 AMIDE DERIVATIVES OF CINNAMIC, FERULIC AND AVENALUMIC SERIES, PROCESS FOR PREPARING SAME AND COSMETIC COMPOSITIONS CONTAINING SAME Produits Chimiques Auxiliaires et de Synthese (FR) 2013-02-13 EP claimed
WO-2011124844-A1 AMIDE DERIVATIVES OF CINNAMIC, FERULIC AND AVENALUMIC SERIES, PROCESS FOR PREPARING SAME AND COSMETIC COMPOSITIONS CONTAINING SAME PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) 2011-10-13 WO claimed
WO-2011019680-A1 PROCESS FOR PREPARING 4-METHYL-3-THIENYLAMINE HYDROCHLORIDE SANOFI-AVENTIS U.S. LLC (US) 2011-02-17 WO claimed
EP-2170872-B1 PROCESS FOR THE PREPARATION OF THE N-(2-CHLORO-4-METHYL-3-THIENYL)-1H- BENZIMIDAZOL-2-AMINE HYDROCHLORIDE AND INTERMEDIATES THEREOF SANOFI AVENTIS US LLC (US) 2010-09-01 EP claimed
US-12522614-B2 Topical phosphoinositide 3-kinase inhibitors VENTHERA, INC. (US) 2026-01-13 US disclosed
EP-4514807-B1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS INC (US) 2025-12-17 EP disclosed
US-20250340570-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS INC (US) 2025-11-06 US disclosed
US-12421243-B2 Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) 2025-09-23 US disclosed
WO-2025093589-A1 HETEROARYL AMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-05-08 WO disclosed
WO-2025093590-A1 HETEROARYL ESTER DERIVATIVES AS SODIUM CHANNEL INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-05-08 WO disclosed
US-5006535-A Substituted heterocylic 4-aminoquinoline derivatives as gastric acid secretion inhibitors SMITH KLINE & FRENCH LABORATORIES LTD. (GB) 1991-04-09 US disclosed
EP-0336544-A1 Heteroaryl 4-amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) 1989-10-11 EP disclosed
US-4866065-A ANTICONVULSANTS, ANXIOLYTIC AGENTS, HYPNOTICS, AND COGNITION ACTIVATORS A/S FERROSAN (DK) 1989-09-12 US disclosed
EP-0227431-A1 Heterocyclic amides BEECHAM GROUP PLC (GB) 1987-07-01 EP disclosed
US-4659707-A ANTIULCER, ANTISECRETORY, ANTIMUSCARINIC AND/OR ANTISPASMODIC AGENTS DOMPE' FARMACEUTICI S.P.A. (IT) 1987-04-21 US disclosed
EP-0213450-A2 Aminoacyl derivatives of 4,9-dihydro-10H-pyrido[3,2-b]-thieno-[3,2-e][1,4]diazepinone and of 4,9-dihydro-10H-pyrido[3,2-b]-thieno[3,4-e][1,4]diazepinone, their preparation and pharmaceutical compositions containing them DOMPE' FARMACEUTICI S.p.A. (IT) 1987-03-11 EP disclosed
US-4139700-A ACID-CATALYZED CYCLIZATION OF SULFAMOYL ACID OR ESTER MONSANTO COMPANY (US) 1979-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340570-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING RBM17, SF3A2, SMN1; SMN2 L3MBTL1 542/4885POLB 397/4885TDP1 493/4885
US-12421243-B2 Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms MYH2, MYLK2, MYO1B L3MBTL1 4080/4885POLB 1490/4885TDP1 1254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.