Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 3/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523467 | 0.84 | GAA (0.54) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL10465688 | 0.81 | ACE (0.57) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL8412255 | 0.80 | ACE (0.57) | TACR1 | |
| SCHEMBL11696472 | 0.80 | OPRK1 (0.66) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL30523437 | 0.79 | GAA (0.54) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL8412088 | 0.77 | PTPN1 (0.49) | GAAALDH1A1TACR1HCRTR2KMT2A | |
| SCHEMBL8411428 | 0.77 | TACR1 (0.57) | GAARAB9ATACR1HCRTR2 | |
| SCHEMBL1793176 | 0.76 | GAA (0.76) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL31206887 | 0.76 | GAA (0.76) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL2461492 | 0.76 | GAA (0.76) | GAARAB9AALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |