Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884012 | 0.92 | ACE (0.55) | ACEGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10449482 | 0.91 | FPR2 (0.63) | ACEALDH1A1SMN1; SMN2LDHAHCRTR2 | |
| SCHEMBL8412092 | 0.91 | FPR2 (0.63) | ACEALDH1A1SMN1; SMN2LDHAHCRTR2 | |
| SCHEMBL7814592 | 0.91 | FPR2 (0.63) | ACEALDH1A1SMN1; SMN2LDHAHCRTR2 | |
| SCHEMBL11699464 | 0.90 | GAA (0.55) | ACEGAARAB9AALDH1A1LMNA | |
| SCHEMBL28607027 | 0.88 | RAB9A (0.63) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL31389141 | 0.88 | RAB9A (0.63) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL26148922 | 0.88 | RAB9A (0.63) | GAARAB9AALDH1A1LMNAGLA | |
| SCHEMBL8412258 | 0.86 | GAA (0.58) | ACEGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1793176 | 0.84 | GAA (0.76) | ACEGAARAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912221-A | Chiral 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and precursors and preparation thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |