Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | GLB1 | P16278 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647219 | 0.88 | APP (0.56) | SMN1; SMN2NPSR1PPARAMAPTFBP1 | |
| SCHEMBL8560277 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL12585031 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL12584997 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL8563621 | 0.78 | FBP1 (0.58) | SMN1; SMN2NPSR1MAPTFBP1APP | |
| SCHEMBL8523609 | 0.77 | SMN1; SMN2 (0.74) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL2032147 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL7506690 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL12585006 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL31038096 | 0.75 | FBP1 (0.74) | SMN1; SMN2NPSR1MAPTFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |
| US-5624937-A | TREATMENT OF ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |