Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 2/20 | 0.41 |
| ▸ | GLB1 | P16278 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575462 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1PPARACTRCGLB1 | |
| SCHEMBL8564013 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL12585006 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL12584997 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL8523609 | 0.71 | SMN1; SMN2 (0.74) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL12585031 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL5713076 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2NPSR1PPARALOXL2CTRC | |
| SCHEMBL2034875 | 0.71 | PPARA (0.49) | SMN1; SMN2NPSR1PPARACTRCGLB1 | |
| SCHEMBL8560277 | 0.70 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1PPARALOXL2IDO1 | |
| SCHEMBL7496577 | 0.70 | PDK1 (0.40) | SMN1; SMN2NPSR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192137-A1 | COMPOUNDS FOR THE MODULATION OF PPAR$g(g) ACTIVITY | Tularik Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001000579-A1 | COMPOUNDS FOR THE MODULATION OF PPARη ACTIVITY | TULARIK INC. (US) | 2001-01-04 | — | — | WO | disclosed |