Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GCGR | P47871 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | AKT2 | P31751 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292890 | 0.87 | NR1I3 (0.53) | ALDH1A1NR1I3PTGS1PTGS2MAPK13 | |
| SCHEMBL9293490 | 0.87 | NR1I3 (0.53) | ALDH1A1NR1I3PTGS1PTGS2MAPK13 | |
| SCHEMBL22342526 | 0.86 | ALDH1A1 (0.61) | ALDH1A1NR1I3MAPK13MAPK12MAPK11 | |
| SCHEMBL22342529 | 0.85 | ALDH1A1 (0.57) | ALDH1A1NR1I3MAPK13MAPK12MAPK11 | |
| SCHEMBL9298472 | 0.82 | CSNK1D (0.58) | ALDH1A1NR1I3MAPK13MAPK12MAPK11 | |
| SCHEMBL8565114 | 0.80 | PTGS2 (0.62) | ALDH1A1NR1I3PTGS1PTGS2MAPK13 | |
| SCHEMBL6102319 | 0.80 | MAPT (0.53) | ALDH1A1PTGS1PTGS2MAPK13MAPK12 | |
| SCHEMBL7217081 | 0.80 | PTGS2 (0.62) | ALDH1A1NR1I3PTGS1PTGS2MAPK13 | |
| SCHEMBL1429286 | 0.79 | ALDH1A1 (0.67) | ALDH1A1NR1I3MAPK13MAPK12MAPK11 | |
| SCHEMBL22342514 | 0.77 | ALDH1A1 (0.54) | ALDH1A1NR1I3MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819127-A1 | IMIDAZO [1,2-a]PYRIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031509-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1996-10-10 | — | — | WO | disclosed |